SLC39A8

GENE INFORMATION

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Gene name

SLC39A8 (HGNC Symbol)

Synonyms

BIGM103

Description

Solute carrier family 39 (zinc transporter), member 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]

Chromosome

4

Cytoband

q24

Chromosome location (bp)

103172198 - 103352415

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000138821 (version 75.37)

Entrez gene

64116

UniProt

Q9C0K1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9C0K1

Antibodypedia

SLC39A8 antibodies
 

PROTEIN VIEW

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SLC39A8-001
 
SLC39A8-002
 
SLC39A8-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC39A8-001 ENSP00000349174
ENST00000356736
Q9C0K1
Show all »
Show » Show » 460 49.6 Yes 6
SLC39A8-002 ENSP00000378310
ENST00000394833
Q9C0K1
Show all »
Show » Show » 460 49.6 Yes 6
SLC39A8-003 ENSP00000394548
ENST00000424970
Q9C0K1
Show all »
Show » Show » 444 48.1 Yes 5